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Symbol
Name
ID
Foxl2
forkhead box L2
MGI:1349428
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Increased circulating gonadotropin level
Disease(s) Associated with FOXL2
blepharophimosis, ptosis, and epicanthus inversus syndrome

Mouse Phenotypes
impaired granulosa cell differentiation
decreased granulosa cell proliferation
abnormal ovary morphology
decreased corpora lutea number
abnormal ovarian follicle morphology
absent mature ovarian follicles
absent primordial ovarian follicles
absent secondary ovarian follicles
increased atretic ovarian follicle number
impaired ovarian folliculogenesis
abnormal ovary size
decreased ovary weight
small ovary
abnormal seminiferous tubule morphology
decreased Sertoli cell number
decreased testis weight
small testis
abnormal ovary physiology
abnormal testis physiology
Availability Mouse Genotype
Foxl2tm1Gpil/Foxl2tm1Gpil
Foxl2tm1Tre/Foxl2tm1Tre
Foxl2tm4(cre)Tre/Foxl2tm4(cre)Tre
Foxl2tm2.1Tre/Foxl2tm2.1Tre
Gt(ROSA)26Sortm9(cre/ESR1)Arte/?  (conditional)
Foxl2tm2.1Tre/Foxl2tm2.1Tre
Tg(Cga-cre)3Sac/0  (conditional)
Foxl2tm2.1Tre/Foxl2tm2.1Tre
Gnrhrtm1.1(cre)Uboe/Gnrhr+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory